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Topical Products

Find soothing relief from itchiness and irritation with our range of topical products, including creams, gels, and sprays. Specially formulated to provide relief from minor skin irritations, insect bites, and allergic reactions, experience the cooling comfort that helps you get back to your daily activities without the distraction of discomfort.

Benadryl topical allergy relief products
Benadryl - Claim - Bought by more households

Bought by more households than any other OTC Allergy brand.

Do not use more than one diphenhydramine product at the same time. Use products only as directed.

Frequently Asked Questions

Oral BENADRYL® Allergy products are meant to be ingested (swallowed). They come in tablet and liquid gel forms and temporarily relieve the symptoms of upper respiratory allergies. Topical BENADRYL® itch relief products are only to be applied directly to the skin. They come in cream, gel, and spray forms, and temporarily relieve itching and pain on the skin. It is important to read labels carefully and follow the instructions for use.

Do NOT swallow a Topical BENADRYL® product. Do NOT use two products containing diphenhydramine at the same time.

Topical BENADRYL® Itch Stopping Cream temporarily relieves pain and itching associated with insect bites, minor burns, sunburn, minor skin irritations, minor cuts, scrapes, and rashes due to poison ivy, poison oak, and poison sumac.

No. Do NOT use multiple products that contain diphenhydramine at the same time, even if one is topical and the other is oral. For information on appropriate dosage and warnings, please review the BENADRYL® product label, available on the packaging or on our website.

It is never safe to take multiple antihistamine medications such as Zyrtec and BENADRYL® or Claritin and BENADRYL® together. Combining BENADRYL® with other antihistamine medications can lead to serious complications or, in rare cases, an antihistamine overdose. If you suspect that you or someone you know is experiencing an antihistamine overdose, immediately call 911 or the poison control helpline at 1-800-222-1222.

No. BENADRYL® Itch Stopping Cream products are not intended to be used on dogs, cats, or any other pets. Please consult your veterinarian if you have questions about your pet’s health needs.

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